Wednesday 15 October 2014

Klinefelter Syndrome.

As i completed constructing my karyotype for a foetus i determined that the karyotype i was working on has a disorder called Klinefelter syndrome.(XXY)

Klinefelter Syndrome can only affect males, its a genetic condition and it means that males have an extra X chromosome. Chromosomes are structures located inside the plant and animal cells. Each chromosome is made out of protein and a single molecule of deoxyribonucleic acid (DNA).Humans have 23 pairs of chromosomes, for a total of 46 chromosomes.
The gain or loss of chromosome material can lead to a variety of genetic disorders as the extra X chromosome Klinefelter syndrome. The symptoms of the disorder (as you can see on figure 1)       are: abnormally large breasts, small testicles and sexual problems.
                                                                     
                                                                       (Figure 1)

Many man with an extra X chromosome are not aware that they have it until reaching puberty. the presence of an extra X chromosome in males often occur when the genetic material in the sperm splits unevenly.
 Men who have Klinefelter syndrome usually could not father children.
But i have found out on This Site that they have found a way for man to father their children.
If a man with Klinefelter syndrome wants to have children, he may be able to have his sperm collected through testicular sperm extraction. 
During test, sperm are obtained using a thin niddle insterted into the testicle or through a small cut made in the testicle. Normal sperm are then identified and used for in Vitro fertilization.

2 comments:

  1. This was a very informative blog on The Klinefelter syndrome. You explained the syndrome very well with scientific terms and the picture helped understand.

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  2. Your blog was giving enough informations about the Klinefelter syndrome. I believe that you should write a bit more about a person with this syndrome. But again, nice work.

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